Professor David Owens

Chair, Biomedical Sciences

+44 (0) 1792 602208

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Fluent Welsh Speaker

Research Links

https://orcid.org/0000-0003-1002-1238

Available For Postgraduate Supervision

About

Professor David R Owens is the Clinical lead for Diabetes Related Retinopathy in the Diabetes Research Group, Swansea University Medical School. He provides support to the MSc Diabetes Practice course and supervision for PhD projects, both in the Unit and elsewhere. He is a regular external examiner of various dissertations both nationally and internationally.

Professor Owens works closely with the International Diabetes Federation in producing educational material on diabetes related eye disease and formulating programmes for future conferences on diabetes complications. He has been involved over many years in supporting the development of diabetes services in a number of developing counti

Areas Of Expertise

Diabetes mellitus
Insulin – pharmacology and clinical applications.
Pathophysiology - type 2 diabetes
Diabetes related retinopathy, foot disease
Screening/management of retinopathy
Literature reviews
Quantitative research methodologies
Data analysis

Career Highlights

Teaching Interests

Professor Owens is a faculty member of the ‘Rising Stars Diabetes Educational programme’ in collaboration with the International Diabetes Center, Minneapolis, USA. Annually, prior to the European Association for the Study of Diabetes meetings a two day meeting is held involving 50-60 doctors invited from across the world to explore advance in diabetes management through lectures and workshops.

Research Award Highlights Collaborations

Publications

Research Highlights

Monnier, L., Colette, C., & Owens, D. (2022). Three Key Indices in Clinical Practice to Better Comprehend the Postprandial and Basal Glucose Contributions in Type 2 Diabetes. Diabetes Technology and Therapeutics, 24(11), 853-855.
https://doi.org/10.1089/dia.2022.0286, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61919
Qu, Y., Zhuo, Y., Lee, J., Huang, X., Yang, Z., Yu, H., Zhang, J., Yuan, W., Wu, J., Owens, D., & Zee, B. (2022). Ischemic and haemorrhagic stroke risk estimation using a machine-learning-based retinal image analysis. Frontiers in Neurology, 13
https://doi.org/10.3389/fneur.2022.916966, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60879
Bolli, G., Cheng, A., & Owens, D. (2022). Insulin: evolution of insulin formulations and their application in clinical practice over 100 years. Acta Diabetologica, 59(9), 1129-1144.
https://doi.org/10.1007/s00592-022-01938-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60647
Landgraf, W., Bigot, G., Hess, S., Asplund, O., Groop, L., Ahlqvist, E., Käräjämäki, A., Owens, D., Frier, B., & Bolli, G. (2022). Distribution and characteristics of newly-defined subgroups of type 2 diabetes in randomised clinical trials: Post hoc cluster assignment analysis of over 12,000 study participants. Diabetes Research and Clinical Practice, 190, 110012
https://doi.org/10.1016/j.diabres.2022.110012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60645
Qu, Y., Lee, J., Zhuo, Y., Liu, S., Thomas, B., Owens, D., & Zee, B. (2022). Risk Assessment of CHD Using Retinal Images with Machine Learning Approaches for People with Cardiometabolic Disorders. Journal of Clinical Medicine, 11(10), 2687
https://doi.org/10.3390/jcm11102687, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60527
Nugawela, M., Gurudas, S., Prevost, A., Mathur, R., Robson, J., Sathish, T., Rafferty, J., Rajalakshmi, R., Anjana, R., Jebarani, S., Mohan, V., Owens, D., & Sivaprasad, S. (2022). Development and validation of predictive risk models for sight threatening diabetic retinopathy in patients with type 2 diabetes to be applied as triage tools in resource limited settings. eClinicalMedicine, 51, 101578
https://doi.org/10.1016/j.eclinm.2022.101578, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60460
Monnier, L., Colette, C., & Owens, D. (2022). Below Which Threshold of Glycemic Variability Is There a Minimal Risk of Hypoglycemia in People with Type 2 Diabetes?. Diabetes Technology & Therapeutics, 24(6), 453-454.
https://doi.org/10.1089/dia.2022.0006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59643
Dunseath, G., Luzio, S., Peter, R., & Owens, D. (2022). The pathophysiology of glucose intolerance in newly diagnosed, untreated T2DM. Acta Diabetologica, 59(2), 207-215.
https://doi.org/10.1007/s00592-021-01785-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60093
Bolli, G., Porcellati, F., Lucidi, P., Fanelli, C., & Owens, D. (2022). One-hundred year evolution of prandial insulin preparations: From animal pancreas extracts to rapid-acting analogs. Metabolism, 126, 154935
https://doi.org/10.1016/j.metabol.2021.154935, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58631
Owens, D., Monnier, L., Ceriello, A., & Bolli, G. (2022). Insulin Centennial: Milestones influencing the development of insulin preparations since 1922. Diabetes, Obesity and Metabolism, 24(S1), 27-42.
https://doi.org/10.1111/dom.14587, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58536
Gurudas, S., Nugawela, M., Prevost, A., Sathish, T., Mathur, R., Rafferty, J., Blighe, K., Rajalakshmi, R., Mohan, A., Saravanan, J., Majeed, A., Mohan, V., Owens, D., Robson, J., Sivaprasad, S., & Group), . (2021). Development and validation of resource-driven risk prediction models for incident chronic kidney disease in type 2 diabetes. Scientific Reports, 11(1)
https://doi.org/10.1038/s41598-021-93096-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58154
Chowdhury, S., Thomas, B., Dunseath, G., Luzio, S., Wong, F., & Owens, D. (2021). Incidence of diabetic retinopathy in newly diagnosed subjects with type 2 diabetes mellitus over 5 years: Contribution of Β-cell function. Journal of Diabetes and its Complications, 36(1), 108028
https://doi.org/10.1016/j.jdiacomp.2021.108028, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57917
Monnier, L., Colette, C., & Owens, D. (2021). Si l'ère des insulines semi-synthétiques et biosynthétiques nous était contée. Médecine des Maladies Métaboliques, 15(3), 3S32-3S52.
https://doi.org/10.1016/s1957-2557(21)00178-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57751
Monnier, L., Owens, D., Colette, C., & Bonnet, F. (2021). Glycaemic variabilities: Key questions in pursuit of clarity. Diabetes & Metabolism, 47(6), 101283
https://doi.org/10.1016/j.diabet.2021.101283, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57749
Thomas, B., Cheung, I., Rafferty, J., Luzio, S., Akbari, A., & Owens, D. (2021). Characteristics of repeat non‐attenders at Diabetes Eye Screening Wales, a national community‐based diabetes‐related retinopathy screening service, during 2003‐2018. Diabetic Medicine, 38(9)
https://doi.org/10.1111/dme.14536, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56211
Rafferty, J., Stephens, J., Atkinson, M., Luzio, S., Akbari, A., Gregory, J., Bain, S., Owens, D., & Thomas, B. (2021). A retrospective epidemiological study of Type 1 Diabetes Mellitus in Wales, UK between 2008 and 2018. International Journal of Population Data Science, 6(1)
https://doi.org/10.23889/ijpds.v6i1.1387, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56716
Monnier, L., Colette, C., & Owens, D. (2021). Glucose variability and diabetes complications: Risk factor or biomarker? Can we disentangle the “Gordian Knot”?. Diabetes & Metabolism, 47(3), 101225
https://doi.org/10.1016/j.diabet.2021.101225, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56025
Rafferty, J., Owens, D., Luzio, S., Watts, P., Akbari, A., & Thomas, B. (2020). Risk factors for having diabetic retinopathy at first screening in persons with type 1 diabetes diagnosed under 18 years of age. Eye, 35
https://doi.org/10.1038/s41433-020-01326-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55801
Nanayakkara, N., Curtis, A., Heritier, S., Gadowski, A., Pavkov, M., Kenealy, T., Owens, D., Thomas, B., Song, S., Wong, J., Chan, J., Luk, A., Penno, G., Ji, L., Mohan, V., Amutha, A., Romero-Aroca, P., Gasevic, D., Magliano, D...., & Zoungas, S. (2021). Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses. Diabetologia, 64(2), 275-287.
https://doi.org/10.1007/s00125-020-05319-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55063
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, W., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48683
Churm, R., Dunseath, G., Prior, S., Thomas, F., Banerjee, S., & Owens, D. (2019). Development and characterization of an in vitro system of the human retina using cultured cell lines. Clinical & Experimental Ophthalmology, 47(8), 1055-1062.
https://doi.org/10.1111/ceo.13578, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50970
Landgraf, W., Owens, D., Frier, B., Zhang, M., & Bolli, G. (n.d.) Fasting C‐peptide, a biomarker for hypoglycaemia risk in insulin‐naïve people with type 2 diabetes initiating basal insulin glargine 100 U/mL. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13897, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52651
http://dx.doi.org/10.1111/dom.13897
Noyel, G., Thomas, B., Iles, S., Bhakta, G., Crowder, A., Owens, D., & Boyle, P. (2019). Registration Of Retinal Images From Public Health By Minimising An Error Between Vessels Using An Affine Model With Radial Distortions. In 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019) (pp. 561-564). IEEE.
https://doi.org/10.1109/isbi.2019.8759415, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52801
Monnier, L., Wojtusciszyn, A., Molinari, N., Colette, C., Renard, E., & Owens, D. (n.d.) Respective Contributions of Glycemic Variability and Mean Daily Glucose as Predictors of Hypoglycemia in Type 1 Diabetes: Are They Equivalent?. Diabetes Care, dc191549
https://doi.org/10.2337/dc19-1549, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53212
Owens, D. & Bolli, G. (2020). The continuing quest for better subcutaneously administered prandial insulins: a review of recent developments and potential clinical implications. Diabetes, Obesity and Metabolism, 22(5), 743-754.
https://doi.org/10.1111/dom.13963, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53215
Campbell, M., Sathish, T., Zimmet, P., Thankappan, K., Oldenburg, B., Owens, D., Shaw, J., & Tapp, R. (2020). Benefit of lifestyle-based T2DM prevention is influenced by prediabetes phenotype. Nature Reviews Endocrinology, 16(7), 395-400.
https://doi.org/10.1038/s41574-019-0316-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53216
Williams, D., Parsons, S., Dunseath, G., Stephens, J., Luzio, S., & Owens, D. (2020). The impact of structured self-monitoring of blood glucose on glycaemic variability in non-insulin treated type 2 diabetes: The SMBG study, a 12-month randomised controlled trial. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(2), 101-106.
https://doi.org/10.1016/j.dsx.2020.01.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53409
Monnier, L., Colette, C., Bonnet, F., & Owens, D. (n.d.) Number Needed-to-Treat (NNT): Is it a necessary marker of therapeutic efficiency?. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2020.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53471
Ceriello, A., deValk, H., Guerci, B., Haak, T., Owens, D., Canobbio, M., Fritzen, K., Stautner, C., & Schnell, O. (2020). The burden of type 2 diabetes in Europe: Current and future aspects of insulin treatment from patient and healthcare spending perspectives. Diabetes Research and Clinical Practice, 161, 108053
https://doi.org/10.1016/j.diabres.2020.108053, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53564
Thomas, B., Winfield, T., Prettyjohns, M., Dunstan, F., Cheung, I., Anderson, P., Peter, R., Luzio, S., Owens, D., & Peter, R. (2020). Cost-effectiveness of biennial screening for diabetes related retinopathy in people with type 1 and type 2 diabetes compared to annual screening. The European Journal of Health Economics
https://doi.org/10.1007/s10198-020-01191-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54012
Bergman, M., Abdul-Ghani, M., DeFronzo, R., Manco, M., Sesti, G., Fiorentino, T., Ceriello, A., Rhee, M., Phillips, L., Chung, S., Cravalho, C., Jagannathan, R., Monnier, L., Colette, C., Owens, D., Bianchi, C., Prato, S., Monteiro, M., Neves, J...., & Buysschaert, M. (2020). Review of methods for detecting glycemic disorders. Diabetes Research and Clinical Practice, 165, 108233
https://doi.org/10.1016/j.diabres.2020.108233, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54315
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, I., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54346
Monnier, L., Colette, C., & Owens, D. (n.d.) Application of medium-term metrics for assessing glucose homoeostasis: Usefulness, strengths and weaknesses. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2020.06.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54460
Lewis, J., Morris, K., Powell, T., Thomas, B., & Owens, D. (2020). Combining diabetic foot and retinopathy screening: A step in the right direction? – a feasibility study. SAGE Open Medicine, 8, 205031212094624
https://doi.org/10.1177/2050312120946244, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54636
Chudleigh, R., Dunseath, G., Peter, R., Dunseath, G., Luzio, S., & Owens, D. (2008). Influence of body weight on the performance of glomerular filtration rate estimators in subjects with type 2 diabetes. Diabetes Care, 31, 47-49.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9922
Chudleigh, R., Ollerton, R., Dunseath, G., Peter, R., Harvey, J., Luzio, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2009). Use of cystatin C-based estimations of glomerular filtration rate in patients with type 2 diabetes. Diabetologia, 52(7), 1274-1278.
https://doi.org/10.1007/s00125-009-1379-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9923
Chudleigh, R., Ollerton, R., Dunseath, G., Peter, R., Harvey, J., Luzio, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2008). Performance of the revised ‘175’ Modification of Diet in Renal Disease equation in patients with type 2 diabetes. Diabetologia, 51(9), 1714-1718.
https://doi.org/10.1007/s00125-008-1086-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10120
Luzio, S., Dunseath, G., Lockett, A., Broke-Smith, T., New, R., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2010). The glucose lowering effect of an oral insulin (Capsulin) during an isoglycaemic clamp study in persons with type 2 diabetes. Diabetes, Obesity and Metabolism, 12(1), 82-87.
https://doi.org/10.1111/j.1463-1326.2009.01146.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10122
Bolli, G., Luzio, S., Marzotti, S., Porcellati, F., Sert-Langeron, C., Charbonnel, B., Zair, Y., Owens, D., Luzio, S., & Owens, D. (2011). Comparative pharmacodynamic and pharmacokinetic characteristics of subcutaneous insulin glulisine and insulin aspart prior to a standard meal in obese subjects with type 2 diabetes. Diabetes, Obesity and Metabolism, 13(3), 251-257.
https://doi.org/10.1111/j.1463-1326.2010.01343.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10123
Ravindran, V., Moore, R., Dunseath, G., Luzio, S., Owens, D., Baboolal, K., & Luzio, S. (2009). Insulin Hyposecretion in Nondiabetic, Tacrolimus-Treated Renal Transplant Recipients More Than 6 months Posttransplantation. Transplantation, 87(12), 1870-1876.
https://doi.org/10.1097/TP.0b013e3181a767b3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10480
http://www.scopus.com/inward/record.url?eid=2-s2.0-67649610585&partnerID=MN8TOARS
Sharif, A., Ravindran, V., Dunseath, G., Luzio, S., Owens, D., Baboolal, K., & Luzio, S. (2010). Impending Hyperglycemia in Normoglycemic Renal Transplant Recipients—An Experimental Predictive Surrogate. Transplantation, 89(11), 1341-1346.
https://doi.org/10.1097/TP.0b013e3181d9e1d8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10973
Peter, R., Dunseath, G., Luzio, S., Chudleigh, R., Choudhury, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2010). Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes. Diabetic Medicine, 27(3), 266-273.
https://doi.org/10.1111/j.1464-5491.2010.02949.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10975
Sharif, A., Ravindran, V., Moore, R., Dunseath, G., Luzio, S., Owens, D., Baboolal, K., & Luzio, S. (2010). Insulin Resistance Indexes in Renal Transplant Recipients Maintained on Tacrolimus Immunosuppression. Transplantation, 89(3), 327-333.
https://doi.org/10.1097/TP.0b013e3181bbf2c4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10976
Peter, R., Dunseath, G., Luzio, S., Chudleigh, R., Choudhury, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2009). Relative and absolute contributions of postprandial and fasting plasma glucose to daytime hyperglycaemia and HbA1cin subjects with Type 2 diabetes. Diabetic Medicine, 26(10), 974-980.
https://doi.org/10.1111/j.1464-5491.2009.02809.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10980
Thomas, R., Dunstan, F., Luzio, S., Chowdhury, S., Hale, S., North, R., Gibbins, R., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2012). Incidence of diabetic retinopathy in people with type 2 diabetes mellitus attending the Diabetic Retinopathy Screening Service for Wales: retrospective analysis. BMJ, 344
https://doi.org/10.1136/bmj.e874, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11753
Yeo, S., Edwards, R., Luzio, S., Charles, J., Thomas, R., Peters, J., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2012). Diabetic retinopathy screening: perspectives of people with diabetes, screening intervals and costs of attending screening. Diabetic Medicine, 29(7), 878-885.
https://doi.org/10.1111/j.1464-5491.2012.03637., SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11754
Yeo, S., Edwards, R., Fargher, E., Luzio, S., Thomas, R., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2012). Preferences of people with diabetes for diabetic retinopathy screening: a discrete Choice experiment. Diabetic Medicine, 29(7), 869-877.
https://doi.org/10.1111/j.1464-5491.2012.03636.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11755
Owens, D., Luzio, S., Sert-Langeron, C., Riddle, M., Luzio, S., & Owens, D. (2011). Effects of initiation and titration of a single pre-prandial dose of insulin glulisine while continuing titrated insulin glargine in type 2 diabetes: a 6-month ‘proof-of-concept' study. Diabetes, Obesity and Metabolism, 13(11), 1020-1027.
https://doi.org/10.1111/j.1463-1326.2011.01459.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12264
Thomas, R., Distiller, L., Luzio, S., Chowdhury, S., Melville, V., Kramer, B., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2013). Ethnic Differences in the Prevalence of Diabetic Retinopathy in Persons With Diabetes When First Presenting at a Diabetes Clinic in South Africa. Diabetes Care, 36(2), 336-341.
https://doi.org/10.2337/dc12-0683, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12272
Sharif, A., Ravindran, V., Moore, R., Baboolal, K., Dunseath, G., Luzio, S., Owens, D., & Luzio, S. (2009). Complex Interplay Between Insulinemia, Glycemia, and Glomerular Filtration Rate in Nondiabetic Renal Transplant Recipients. Transplantation, 88(2), 290-292.
https://doi.org/10.1097/TP.0b013e3181acc901, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12479
Conley, E., Owens, D., Luzio, S., Subramanian, M., Ali, A., Hardisty, A., & Rana, O. (2008). Simultaneous trend analysis for evaluating outcomes in patient-centred health monitoring services. Health Care Management Science, 11(2), 152-166.
https://doi.org/10.1007/s10729-008-9061-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12481
Luzio, S., Peter, R., Dunseath, G., Mustafa, L., & Owens, D. (2008). A comparison of preprandial insulin glulisine versus insulin lispro in people with Type 2 diabetes over a 12-h period. Diabetes Research and Clinical Practice, 79(2), 269-275.
https://doi.org/10.1016/j.diabres.2007.11.013, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12482
Thomas, R., Dunstan, F., Luzio, S., Chowdhury, S., North, R., Hale, S., Gibbins, R., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2015). Prevalence of diabetic retinopathy within a national diabetic retinopathy screening service. British Journal of Ophthalmology, 99(1), 64-68.
https://doi.org/10.1136/bjophthalmol-2013-304017, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18187
http://bjo.bmj.com/content/99/1/64.abstract
Thomas, R., Distiller, L., Luzio, S., Melville, V., Roy Chowdhury, S., Kramer, B., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2015). Incidence and progression of diabetic retinopathy within a private diabetes mellitus clinic in South Africa. Journal of Endocrinology, Metabolism and Diabetes of South Africa, 20(3), 127-133.
https://doi.org/10.1080/16089677.2015.1090159, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa23547
Harvey, J., Owens, D., & Thomas, B. (2016). When should screening for diabetic retinopathy begin for children with type 1 diabetes?. Expert Review of Endocrinology & Metabolism, 11(2), 97-102.
https://doi.org/10.1586/17446651.2016.1145542, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25942
Chowdhury, S., Dunseath, G., Peter, R., Rees, D., North, R., Luzio, S., Owens, D., & Thomas, B. (2016). Diabetic Retinopathy in Newly Diagnosed Subjects With Type 2 Diabetes Mellitus: Contribution of β-Cell Function. The Journal of Clinical Endocrinology & Metabolism, 101(2), 572-580.
https://doi.org/10.1210/jc.2015-2203, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25955
Monnier, L., Colette, C., Schlienger, J., Bauduceau, B., R Owens, D., & Owens, D. (2019). Glucocentric risk factors for macrovascular complications in diabetes: Glucose ‘legacy’ and ‘variability’-what we see, know and try to comprehend. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2019.01.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48942
Ceriello, A., Monnier, L., & Owens, D. (2018). Glycaemic variability in diabetes: clinical and therapeutic implications. The Lancet Diabetes & Endocrinology
https://doi.org/10.1016/S2213-8587(18)30136-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa47993
Owens, D., Landgraf, W., Frier, B., Zhang, M., Home, P., Meneghini, L., & Bolli, G. (2019). Commencing insulin glargine 100 U/mL therapy in individuals with type 2 diabetes: Determinants of achievement of HbA1c goal less than 7.0%. Diabetes, Obesity and Metabolism, 21(2), 321-329.
https://doi.org/10.1111/dom.13607, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46180
Owens, D., S Bailey, T., Fanelli, C., Yale, J., Bolli, G., & Owens, D. (2018). Clinical relevance of pharmacokinetic and pharmacodynamic profiles of insulin degludec (100, 200 U/mL) and insulin glargine (100, 300 U/mL) – a review of evidence and clinical interpretation. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2018.11.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46120
Frier, B., Landgraf, W., Zhang, M., Bolli, G., & Owens, D. (2018). Hypoglycaemia risk in the first 8 weeks of titration with insulin glargine 100 U/mL in previously insulin-naive individuals with type 2 diabetes mellitus. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13450, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa41046
Monnier, L., Colette, C., Owens, D., & Owens, D. (2017). Glucose variability: Do we have to revisit the profusion of definitions to avoid confusion?. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2017.10.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36625
Holden, S., Currie, C., & Owens, D. (2017). Health-economic evaluation of fluocinolone acetonide 190 µg implant in people with diabetic macular edema. Current Medical Research and Opinion, 1-8.
https://doi.org/10.1080/03007995.2017.1366663, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35086
Currie, C., Holden, S., & Owens, D. (2017). Patterns of retinal thickness prior to and following treatment with fluocinolone acetonide 190 µg intravitreal implant for diabetic macular edema. Current Medical Research and Opinion, 1-11.
https://doi.org/10.1080/03007995.2017.1366662, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35085
Currie, C., Holden, S., Berni, E., & Owens, D. (2017). Evaluation of the clinical effectiveness of fluocinolone acetonide 190 µg intravitreal implant in diabetic macular edema: a comparison between study and fellow eyes. Current Medical Research and Opinion, 1-13.
https://doi.org/10.1080/03007995.2017.1366659, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35084
Holden, S., Currie, C., & Owens, D. (2017). Evaluation of the clinical effectiveness in routine practice of fluocinolone acetonide 190 µg intravitreal implant in people with diabetic macular edema. Current Medical Research and Opinion, 1-13.
https://doi.org/10.1080/03007995.2017.1366645, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35083
Xu, W., Owens, D., & Weng, J. (2014). Short-Term Intensive Insulin Therapy in Persons with Newly Presenting Type 2 Diabetes Mellitus. Endocrine and Metabolic Medical Emergencies: A Clinician's Guide-278). Endocrine Press
https://doi.org/10.1210/EME.9781936704811.ch27, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34718
http://press.endocrine.org/doi/book/10.1210/EME.9781936704811
Lorenz, M., Lawson, F., Owens, D., Raccah, D., Roy-Duval, C., Lehmann, A., Perfetti, R., & Blonde, L. (2017). Differential effects of glucagon-like peptide-1 receptor agonists on heart rate. Cardiovascular Diabetology, 16(1)
https://doi.org/10.1186/s12933-016-0490-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31573
Owens, D., Landgraf, W., Sandow, J., & Mbanya, J. (2017). Recombinant Human Insulin in Global Diabetes Management – Focus on Clinical Efficacy. European Endocrinology, 13(01), 21
https://doi.org/10.17925/EE.2017.13.01.21, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33008
Owens, D., Bolli, G., Charbonnel, B., Haak, T., Landgraf, W., Porcellati, F., Traylor, L., & Kautzky-Willer, A. (2017). Effects of age, gender, and body mass index on efficacy and hypoglycaemia outcomes across treat-to-target trials with insulin glargine 100 U/mL added to oral antidiabetes agents in type 2 diabetes. Diabetes, Obesity and Metabolism, 19(11), 1546-1554.
https://doi.org/10.1111/dom.12966, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33019
Owens, D., Monnier, L., Barnett, A., & Owens, D. (2017). Future challenges and therapeutic opportunities in type 2 diabetes: changing the paradigm of current therapy. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.12977, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33119
Owens, D., Monnier, L., Hanefeld, M., & Owens, D. (2017). A review of glucagon-like peptide-1 receptor agonists and their effects on lowering postprandial plasma glucose and cardiovascular outcomes in the treatment of type 2 diabetes mellitus. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.12998, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33249
Monnier, L., Colette, C., & Owens, D. (2016). Comment on the FLAT-SUGAR Trial Investigators. Glucose Variability in a 26-Week Randomized Comparison of Mealtime Treatment With Rapid-Acting Insulin Versus GLP-1 Agonist in Participants With Type 2 Diabetes at High Cardiovascular Risk. Diabetes Care 2016;39:973–981. Diabetes Care, 39(10), e186-e187.
https://doi.org/10.2337/dc16-1133, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33716
Parsons, S., Luzio, S., Bain, S., Harvey, J., McKenna, J., Khan, A., Rice, S., Watkins, A., Owens, D., & Bain, S. (2017). Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial. BMC Endocrine Disorders, 17(1)
https://doi.org/10.1186/s12902-017-0154-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32118
Monnier, L., Colette, C., Wojtusciszyn, A., Dejager, S., Renard, E., Molinari, N., & Owens, D. (2016). Toward Defining the Threshold Between Low and High Glucose Variability in Diabetes. Diabetes Care, dc161769
https://doi.org/10.2337/dc16-1769, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31333
Hanefeld, M., Monnier, L., Schnell, O., & Owens, D. (2016). Early Treatment with Basal Insulin Glargine in People with Type 2 Diabetes: Lessons from ORIGIN and Other Cardiovascular Trials. Diabetes Therapy, 7(2), 187-201.
https://doi.org/10.1007/s13300-016-0153-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26162
Monnier, L., Colette, C., Dejager, S., Owens, D., & Owens, D. (2016). Near normal HbA1c with stable glucose homeostasis: the ultimate target/aim of diabetes therapy. Reviews in Endocrine and Metabolic Disorders, 17(1), 91-101.
https://doi.org/10.1007/s11154-016-9325-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26445
Lankisch, M., Del Prato, S., Dain, M., Mullins, P., & Owens, D. (2016). Use of a basal-plus insulin regimen in persons with type 2 diabetes stratified by age and body mass index: A pooled analysis of four clinical trials. Primary Care Diabetes, 10(1), 51-59.
https://doi.org/10.1016/j.pcd.2015.05.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26720
Inagaki, N., Sheu, W., Owens, D., Crowe, S., Bhandari, A., Gong, Y., & Patel, S. (2016). Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials. Journal of Diabetes and its Complications, 30(8), 1622-1630.
https://doi.org/10.1016/j.jdiacomp.2016.07.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28025
Owens, D. (2016). Pharmacokinetics and pharmacodynamics of insulin glargine 300 U/mL in the treatment of diabetes and their clinical relevance. Expert Opinion on Drug Metabolism & Toxicology, 12(8), 977-987.
https://doi.org/10.1080/17425255.2016.1202916, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28026
Inagaki, N., Sheu, W., Owens, D., Crowe, S., Bhandari, A., Gong, Y., & Patel, S. (2016). Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials. Journal of Diabetes and its Complications, 30(8), 1622-1630.
https://doi.org/10.1016/j.jdiacomp.2016.07.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa29221
Owens, D., Traylor, L., Mullins, P., & Landgraf, W. (2016). Patient-level meta-analysis of efficacy and hypoglycaemia in people with type 2 diabetes initiating insulin glargine 100 U/mL or neutral protamine Hagedorn insulin analysed according to concomitant oral antidiabetes therapy. Diabetes Research and Clinical Practice
https://doi.org/10.1016/j.diabres.2016.10.022, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31168
Monnier, L., Colette, C., Dejager, S., Owens, D., & Owens, D. (2015). The dawn phenomenon in type 2 diabetes: How to assess it in clinical practice?. Diabetes & Metabolism, 41(2), 132-137.
https://doi.org/10.1016/j.diabet.2014.10.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27112
Monnier, L., Colette, C., Dejager, S., & Owens, D. (2015). “Mild dysglycemia” in type 2 diabetes: to be neglected or not?. Journal of Diabetes and its Complications, 29(3), 451-458.
https://doi.org/10.1016/j.jdiacomp.2014.12.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26721
Chan, J., Aschner, P., Owens, D., Picard, S., Vincent, M., Dain, M., Pilorget, V., Loizeau, V., Echtay, A., & Fonseca, V. (2015). Triple combination of insulin glargine, sitagliptin and metformin in type 2 diabetes: The EASIE post-hoc analysis and extension trial. Journal of Diabetes and its Complications, 29(1), 134-141.
https://doi.org/10.1016/j.jdiacomp.2014.08.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26722
Hilgenfeld, R., Seipke, G., Berchtold, H., & Owens, D. (2014). The Evolution of Insulin Glargine and its Continuing Contribution to Diabetes Care. Drugs, 74(8), 911-927.
https://doi.org/10.1007/s40265-014-0226-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26725
Groop, P., Del Prato, S., Taskinen, M., Owens, D., Gong, Y., Crowe, S., Patel, S., von Eynatten, M., Woerle, H., & Owens, D. (2014). Linagliptin treatment in subjects with type 2 diabetes with and without mild-to-moderate renal impairment. Diabetes, Obesity and Metabolism, 16(6), 560-568.
https://doi.org/10.1111/dom.12281, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26726
Bolli, G., Owens, D., & Owens, D. (2014). Lixisenatide, a novel GLP-1 receptor agonist: efficacy, safety and clinical implications for type 2 diabetes mellitus. Diabetes, Obesity and Metabolism, 16(7), 588-601.
https://doi.org/10.1111/dom.12253, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26727
Thomas, R., Prior, S., Barry, J., Luzio, S., Eyre, N., Caplin, S., Stephens, J., Owens, D., & Thomas, B. (2014). Does bariatric surgery adversely impact on diabetic retinopathy in persons with morbid obesity and type 2 diabetes? A pilot study. Journal of Diabetes and its Complications, 28(2), 191-195.
https://doi.org/10.1016/j.jdiacomp.2013.10.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26728
Monnier, L., Colette, C., Dejager, S., Owens, D., & Owens, D. (2014). Residual dysglycemia when at target HbA1c of 7% (53mmol/mol) in persons with type 2 diabetes. Diabetes Research and Clinical Practice, 104(3), 370-375.
https://doi.org/10.1016/j.diabres.2014.03.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27111
Owens, D., Traylor, L., Dain, M., & Landgraf, W. (2014). Efficacy and safety of basal insulin glargine 12 and 24 weeks after initiation in persons with type 2 diabetes: A pooled analysis of data from treatment arms of 15 treat-to-target randomised controlled trials. Diabetes Research and Clinical Practice, 106(2), 264-274.
https://doi.org/10.1016/j.diabres.2014.08.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26723
Owens, D., Matfin, G., & Monnier, L. (2014). Basal insulin analogues in the management of diabetes mellitus: what progress have we made?. Diabetes/Metabolism Research and Reviews, 30(2), 104-119.
https://doi.org/10.1002/dmrr.2469, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27113
Owens, D. (2014). Guideline for management of postmeal glucose in diabetes. Diabetes Research and Clinical Practice, 103(2), 256-268.
https://doi.org/10.1016/j.diabres.2012.08.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27114
Owens, D., Landgraf, W., Schmidt, A., Bretzel, R., & Kuhlmann, M. (2012). The Emergence of Biosimilar Insulin Preparations—A Cause for Concern?. Diabetes Technology Therapeutics, 14(11), 989-996.
https://doi.org/10.1089/dia.2012.0105, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13257
Owens, D., Prato, S., Taskinen, M., Gomis, R., Forst, T., Woerle, H., & Owens, D. (2012). Response Letter to D. Singh-Franco et al.. Diabetes, Obesity and Metabolism, 14(11), 1054-1055.
https://doi.org/10.1111/j.1463-1326.2012.01623.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13258
Owens, D. & Owens, D. (2012). Stepwise intensification of insulin therapy in Type 2 diabetes management-exploring the concept of the basal-plus approach in clinical practice. Diabetic Medicine, n/a-n/a.
https://doi.org/10.1111/dme.12019, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13268

All Research

Journal Articles

Monnier, L., Colette, C., & Owens, D. (2022). Three Key Indices in Clinical Practice to Better Comprehend the Postprandial and Basal Glucose Contributions in Type 2 Diabetes. Diabetes Technology and Therapeutics, 24(11), 853-855.
https://doi.org/10.1089/dia.2022.0286, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61919
Bolli, G., Cheng, A., & Owens, D. (2022). Insulin: evolution of insulin formulations and their application in clinical practice over 100 years. Acta Diabetologica, 59(9), 1129-1144.
https://doi.org/10.1007/s00592-022-01938-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60647
Nugawela, M., Gurudas, S., Prevost, A., Mathur, R., Robson, J., Sathish, T., Rafferty, J., Rajalakshmi, R., Anjana, R., Jebarani, S., Mohan, V., Owens, D., & Sivaprasad, S. (2022). Development and validation of predictive risk models for sight threatening diabetic retinopathy in patients with type 2 diabetes to be applied as triage tools in resource limited settings. eClinicalMedicine, 51, 101578
https://doi.org/10.1016/j.eclinm.2022.101578, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60460
Qu, Y., Zhuo, Y., Lee, J., Huang, X., Yang, Z., Yu, H., Zhang, J., Yuan, W., Wu, J., Owens, D., & Zee, B. (2022). Ischemic and haemorrhagic stroke risk estimation using a machine-learning-based retinal image analysis. Frontiers in Neurology, 13
https://doi.org/10.3389/fneur.2022.916966, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60879
Landgraf, W., Bigot, G., Hess, S., Asplund, O., Groop, L., Ahlqvist, E., Käräjämäki, A., Owens, D., Frier, B., & Bolli, G. (2022). Distribution and characteristics of newly-defined subgroups of type 2 diabetes in randomised clinical trials: Post hoc cluster assignment analysis of over 12,000 study participants. Diabetes Research and Clinical Practice, 190, 110012
https://doi.org/10.1016/j.diabres.2022.110012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60645
Monnier, L., Colette, C., & Owens, D. (2022). Below Which Threshold of Glycemic Variability Is There a Minimal Risk of Hypoglycemia in People with Type 2 Diabetes?. Diabetes Technology & Therapeutics, 24(6), 453-454.
https://doi.org/10.1089/dia.2022.0006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59643
Qu, Y., Lee, J., Zhuo, Y., Liu, S., Thomas, B., Owens, D., & Zee, B. (2022). Risk Assessment of CHD Using Retinal Images with Machine Learning Approaches for People with Cardiometabolic Disorders. Journal of Clinical Medicine, 11(10), 2687
https://doi.org/10.3390/jcm11102687, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60527
Dunseath, G., Luzio, S., Peter, R., & Owens, D. (2022). The pathophysiology of glucose intolerance in newly diagnosed, untreated T2DM. Acta Diabetologica, 59(2), 207-215.
https://doi.org/10.1007/s00592-021-01785-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa60093
Owens, D., Monnier, L., Ceriello, A., & Bolli, G. (2022). Insulin Centennial: Milestones influencing the development of insulin preparations since 1922. Diabetes, Obesity and Metabolism, 24(S1), 27-42.
https://doi.org/10.1111/dom.14587, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58536
Bolli, G., Porcellati, F., Lucidi, P., Fanelli, C., & Owens, D. (2022). One-hundred year evolution of prandial insulin preparations: From animal pancreas extracts to rapid-acting analogs. Metabolism, 126, 154935
https://doi.org/10.1016/j.metabol.2021.154935, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58631
Monnier, L., Owens, D., Colette, C., & Bonnet, F. (2021). Glycaemic variabilities: Key questions in pursuit of clarity. Diabetes & Metabolism, 47(6), 101283
https://doi.org/10.1016/j.diabet.2021.101283, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57749
Thomas, B., Cheung, I., Rafferty, J., Luzio, S., Akbari, A., & Owens, D. (2021). Characteristics of repeat non‐attenders at Diabetes Eye Screening Wales, a national community‐based diabetes‐related retinopathy screening service, during 2003‐2018. Diabetic Medicine, 38(9)
https://doi.org/10.1111/dme.14536, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56211
Chowdhury, S., Thomas, B., Dunseath, G., Luzio, S., Wong, F., & Owens, D. (2021). Incidence of diabetic retinopathy in newly diagnosed subjects with type 2 diabetes mellitus over 5 years: Contribution of Β-cell function. Journal of Diabetes and its Complications, 36(1), 108028
https://doi.org/10.1016/j.jdiacomp.2021.108028, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57917
Gurudas, S., Nugawela, M., Prevost, A., Sathish, T., Mathur, R., Rafferty, J., Blighe, K., Rajalakshmi, R., Mohan, A., Saravanan, J., Majeed, A., Mohan, V., Owens, D., Robson, J., Sivaprasad, S., & Group), . (2021). Development and validation of resource-driven risk prediction models for incident chronic kidney disease in type 2 diabetes. Scientific Reports, 11(1)
https://doi.org/10.1038/s41598-021-93096-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa58154
Monnier, L., Colette, C., & Owens, D. (2021). Si l'ère des insulines semi-synthétiques et biosynthétiques nous était contée. Médecine des Maladies Métaboliques, 15(3), 3S32-3S52.
https://doi.org/10.1016/s1957-2557(21)00178-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57751
Monnier, L., Colette, C., & Owens, D. (2021). Glucose variability and diabetes complications: Risk factor or biomarker? Can we disentangle the “Gordian Knot”?. Diabetes & Metabolism, 47(3), 101225
https://doi.org/10.1016/j.diabet.2021.101225, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56025
Rafferty, J., Stephens, J., Atkinson, M., Luzio, S., Akbari, A., Gregory, J., Bain, S., Owens, D., & Thomas, B. (2021). A retrospective epidemiological study of Type 1 Diabetes Mellitus in Wales, UK between 2008 and 2018. International Journal of Population Data Science, 6(1)
https://doi.org/10.23889/ijpds.v6i1.1387, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56716
Nanayakkara, N., Curtis, A., Heritier, S., Gadowski, A., Pavkov, M., Kenealy, T., Owens, D., Thomas, B., Song, S., Wong, J., Chan, J., Luk, A., Penno, G., Ji, L., Mohan, V., Amutha, A., Romero-Aroca, P., Gasevic, D., Magliano, D...., & Zoungas, S. (2021). Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses. Diabetologia, 64(2), 275-287.
https://doi.org/10.1007/s00125-020-05319-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55063
Rafferty, J., Owens, D., Luzio, S., Watts, P., Akbari, A., & Thomas, B. (2020). Risk factors for having diabetic retinopathy at first screening in persons with type 1 diabetes diagnosed under 18 years of age. Eye, 35
https://doi.org/10.1038/s41433-020-01326-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55801
Campbell, M., Sathish, T., Zimmet, P., Thankappan, K., Oldenburg, B., Owens, D., Shaw, J., & Tapp, R. (2020). Benefit of lifestyle-based T2DM prevention is influenced by prediabetes phenotype. Nature Reviews Endocrinology, 16(7), 395-400.
https://doi.org/10.1038/s41574-019-0316-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53216
Bergman, M., Abdul-Ghani, M., DeFronzo, R., Manco, M., Sesti, G., Fiorentino, T., Ceriello, A., Rhee, M., Phillips, L., Chung, S., Cravalho, C., Jagannathan, R., Monnier, L., Colette, C., Owens, D., Bianchi, C., Prato, S., Monteiro, M., Neves, J...., & Buysschaert, M. (2020). Review of methods for detecting glycemic disorders. Diabetes Research and Clinical Practice, 165, 108233
https://doi.org/10.1016/j.diabres.2020.108233, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54315
Thomas, B., Winfield, T., Prettyjohns, M., Dunstan, F., Cheung, I., Anderson, P., Peter, R., Luzio, S., Owens, D., & Peter, R. (2020). Cost-effectiveness of biennial screening for diabetes related retinopathy in people with type 1 and type 2 diabetes compared to annual screening. The European Journal of Health Economics
https://doi.org/10.1007/s10198-020-01191-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54012
Owens, D. & Bolli, G. (2020). The continuing quest for better subcutaneously administered prandial insulins: a review of recent developments and potential clinical implications. Diabetes, Obesity and Metabolism, 22(5), 743-754.
https://doi.org/10.1111/dom.13963, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53215
Williams, D., Parsons, S., Dunseath, G., Stephens, J., Luzio, S., & Owens, D. (2020). The impact of structured self-monitoring of blood glucose on glycaemic variability in non-insulin treated type 2 diabetes: The SMBG study, a 12-month randomised controlled trial. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(2), 101-106.
https://doi.org/10.1016/j.dsx.2020.01.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53409
Ceriello, A., deValk, H., Guerci, B., Haak, T., Owens, D., Canobbio, M., Fritzen, K., Stautner, C., & Schnell, O. (2020). The burden of type 2 diabetes in Europe: Current and future aspects of insulin treatment from patient and healthcare spending perspectives. Diabetes Research and Clinical Practice, 161, 108053
https://doi.org/10.1016/j.diabres.2020.108053, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53564
Lewis, J., Morris, K., Powell, T., Thomas, B., & Owens, D. (2020). Combining diabetic foot and retinopathy screening: A step in the right direction? – a feasibility study. SAGE Open Medicine, 8, 205031212094624
https://doi.org/10.1177/2050312120946244, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54636
Monnier, L., Colette, C., Schlienger, J., Bauduceau, B., R Owens, D., & Owens, D. (2019). Glucocentric risk factors for macrovascular complications in diabetes: Glucose ‘legacy’ and ‘variability’-what we see, know and try to comprehend. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2019.01.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48942
Churm, R., Dunseath, G., Prior, S., Thomas, F., Banerjee, S., & Owens, D. (2019). Development and characterization of an in vitro system of the human retina using cultured cell lines. Clinical & Experimental Ophthalmology, 47(8), 1055-1062.
https://doi.org/10.1111/ceo.13578, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50970
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, W., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48683
Parsons, S., Luzio, S., Harvey, J., Bain, S., Cheung, I., Watkins, A., & Owens, D. (2019). Effect of structured self‐monitoring of blood glucose, with and without additional TeleCare support, on overall glycaemic control in non‐insulin treated Type 2 diabetes: the SMBG Study, a 12‐month randomized controlled trial. Diabetic Medicine, 36(5), 578-590.
https://doi.org/10.1111/dme.13899, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54346
Owens, D., Landgraf, W., Frier, B., Zhang, M., Home, P., Meneghini, L., & Bolli, G. (2019). Commencing insulin glargine 100 U/mL therapy in individuals with type 2 diabetes: Determinants of achievement of HbA1c goal less than 7.0%. Diabetes, Obesity and Metabolism, 21(2), 321-329.
https://doi.org/10.1111/dom.13607, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46180
Ceriello, A., Monnier, L., & Owens, D. (2018). Glycaemic variability in diabetes: clinical and therapeutic implications. The Lancet Diabetes & Endocrinology
https://doi.org/10.1016/S2213-8587(18)30136-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa47993
Owens, D., S Bailey, T., Fanelli, C., Yale, J., Bolli, G., & Owens, D. (2018). Clinical relevance of pharmacokinetic and pharmacodynamic profiles of insulin degludec (100, 200 U/mL) and insulin glargine (100, 300 U/mL) – a review of evidence and clinical interpretation. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2018.11.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa46120
Frier, B., Landgraf, W., Zhang, M., Bolli, G., & Owens, D. (2018). Hypoglycaemia risk in the first 8 weeks of titration with insulin glargine 100 U/mL in previously insulin-naive individuals with type 2 diabetes mellitus. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13450, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa41046
Holden, S., Currie, C., & Owens, D. (2017). Health-economic evaluation of fluocinolone acetonide 190 µg implant in people with diabetic macular edema. Current Medical Research and Opinion, 1-8.
https://doi.org/10.1080/03007995.2017.1366663, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35086
Currie, C., Holden, S., & Owens, D. (2017). Patterns of retinal thickness prior to and following treatment with fluocinolone acetonide 190 µg intravitreal implant for diabetic macular edema. Current Medical Research and Opinion, 1-11.
https://doi.org/10.1080/03007995.2017.1366662, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35085
Currie, C., Holden, S., Berni, E., & Owens, D. (2017). Evaluation of the clinical effectiveness of fluocinolone acetonide 190 µg intravitreal implant in diabetic macular edema: a comparison between study and fellow eyes. Current Medical Research and Opinion, 1-13.
https://doi.org/10.1080/03007995.2017.1366659, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35084
Holden, S., Currie, C., & Owens, D. (2017). Evaluation of the clinical effectiveness in routine practice of fluocinolone acetonide 190 µg intravitreal implant in people with diabetic macular edema. Current Medical Research and Opinion, 1-13.
https://doi.org/10.1080/03007995.2017.1366645, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa35083
Lorenz, M., Lawson, F., Owens, D., Raccah, D., Roy-Duval, C., Lehmann, A., Perfetti, R., & Blonde, L. (2017). Differential effects of glucagon-like peptide-1 receptor agonists on heart rate. Cardiovascular Diabetology, 16(1)
https://doi.org/10.1186/s12933-016-0490-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31573
Owens, D., Bolli, G., Charbonnel, B., Haak, T., Landgraf, W., Porcellati, F., Traylor, L., & Kautzky-Willer, A. (2017). Effects of age, gender, and body mass index on efficacy and hypoglycaemia outcomes across treat-to-target trials with insulin glargine 100 U/mL added to oral antidiabetes agents in type 2 diabetes. Diabetes, Obesity and Metabolism, 19(11), 1546-1554.
https://doi.org/10.1111/dom.12966, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33019
Owens, D., Monnier, L., Barnett, A., & Owens, D. (2017). Future challenges and therapeutic opportunities in type 2 diabetes: changing the paradigm of current therapy. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.12977, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33119
Owens, D., Monnier, L., Hanefeld, M., & Owens, D. (2017). A review of glucagon-like peptide-1 receptor agonists and their effects on lowering postprandial plasma glucose and cardiovascular outcomes in the treatment of type 2 diabetes mellitus. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.12998, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33249
Owens, D., Landgraf, W., Sandow, J., & Mbanya, J. (2017). Recombinant Human Insulin in Global Diabetes Management – Focus on Clinical Efficacy. European Endocrinology, 13(01), 21
https://doi.org/10.17925/EE.2017.13.01.21, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33008
Monnier, L., Colette, C., Owens, D., & Owens, D. (2017). Glucose variability: Do we have to revisit the profusion of definitions to avoid confusion?. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2017.10.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36625
Parsons, S., Luzio, S., Bain, S., Harvey, J., McKenna, J., Khan, A., Rice, S., Watkins, A., Owens, D., & Bain, S. (2017). Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial. BMC Endocrine Disorders, 17(1)
https://doi.org/10.1186/s12902-017-0154-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32118
Harvey, J., Owens, D., & Thomas, B. (2016). When should screening for diabetic retinopathy begin for children with type 1 diabetes?. Expert Review of Endocrinology & Metabolism, 11(2), 97-102.
https://doi.org/10.1586/17446651.2016.1145542, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25942
Monnier, L., Colette, C., Wojtusciszyn, A., Dejager, S., Renard, E., Molinari, N., & Owens, D. (2016). Toward Defining the Threshold Between Low and High Glucose Variability in Diabetes. Diabetes Care, dc161769
https://doi.org/10.2337/dc16-1769, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31333
Inagaki, N., Sheu, W., Owens, D., Crowe, S., Bhandari, A., Gong, Y., & Patel, S. (2016). Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials. Journal of Diabetes and its Complications, 30(8), 1622-1630.
https://doi.org/10.1016/j.jdiacomp.2016.07.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28025
Owens, D. (2016). Pharmacokinetics and pharmacodynamics of insulin glargine 300 U/mL in the treatment of diabetes and their clinical relevance. Expert Opinion on Drug Metabolism & Toxicology, 12(8), 977-987.
https://doi.org/10.1080/17425255.2016.1202916, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28026
Inagaki, N., Sheu, W., Owens, D., Crowe, S., Bhandari, A., Gong, Y., & Patel, S. (2016). Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials. Journal of Diabetes and its Complications, 30(8), 1622-1630.
https://doi.org/10.1016/j.jdiacomp.2016.07.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa29221
Owens, D., Traylor, L., Mullins, P., & Landgraf, W. (2016). Patient-level meta-analysis of efficacy and hypoglycaemia in people with type 2 diabetes initiating insulin glargine 100 U/mL or neutral protamine Hagedorn insulin analysed according to concomitant oral antidiabetes therapy. Diabetes Research and Clinical Practice
https://doi.org/10.1016/j.diabres.2016.10.022, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31168
Monnier, L., Colette, C., & Owens, D. (2016). Comment on the FLAT-SUGAR Trial Investigators. Glucose Variability in a 26-Week Randomized Comparison of Mealtime Treatment With Rapid-Acting Insulin Versus GLP-1 Agonist in Participants With Type 2 Diabetes at High Cardiovascular Risk. Diabetes Care 2016;39:973–981. Diabetes Care, 39(10), e186-e187.
https://doi.org/10.2337/dc16-1133, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa33716
Hanefeld, M., Monnier, L., Schnell, O., & Owens, D. (2016). Early Treatment with Basal Insulin Glargine in People with Type 2 Diabetes: Lessons from ORIGIN and Other Cardiovascular Trials. Diabetes Therapy, 7(2), 187-201.
https://doi.org/10.1007/s13300-016-0153-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26162
Monnier, L., Colette, C., Dejager, S., Owens, D., & Owens, D. (2016). Near normal HbA1c with stable glucose homeostasis: the ultimate target/aim of diabetes therapy. Reviews in Endocrine and Metabolic Disorders, 17(1), 91-101.
https://doi.org/10.1007/s11154-016-9325-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26445
Lankisch, M., Del Prato, S., Dain, M., Mullins, P., & Owens, D. (2016). Use of a basal-plus insulin regimen in persons with type 2 diabetes stratified by age and body mass index: A pooled analysis of four clinical trials. Primary Care Diabetes, 10(1), 51-59.
https://doi.org/10.1016/j.pcd.2015.05.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26720
Chowdhury, S., Dunseath, G., Peter, R., Rees, D., North, R., Luzio, S., Owens, D., & Thomas, B. (2016). Diabetic Retinopathy in Newly Diagnosed Subjects With Type 2 Diabetes Mellitus: Contribution of β-Cell Function. The Journal of Clinical Endocrinology & Metabolism, 101(2), 572-580.
https://doi.org/10.1210/jc.2015-2203, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25955
Thomas, R., Dunstan, F., Luzio, S., Chowdhury, S., North, R., Hale, S., Gibbins, R., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2015). Prevalence of diabetic retinopathy within a national diabetic retinopathy screening service. British Journal of Ophthalmology, 99(1), 64-68.
https://doi.org/10.1136/bjophthalmol-2013-304017, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18187
http://bjo.bmj.com/content/99/1/64.abstract
Monnier, L., Colette, C., Dejager, S., Owens, D., & Owens, D. (2015). The dawn phenomenon in type 2 diabetes: How to assess it in clinical practice?. Diabetes & Metabolism, 41(2), 132-137.
https://doi.org/10.1016/j.diabet.2014.10.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27112
Monnier, L., Colette, C., Dejager, S., & Owens, D. (2015). “Mild dysglycemia” in type 2 diabetes: to be neglected or not?. Journal of Diabetes and its Complications, 29(3), 451-458.
https://doi.org/10.1016/j.jdiacomp.2014.12.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26721
Chan, J., Aschner, P., Owens, D., Picard, S., Vincent, M., Dain, M., Pilorget, V., Loizeau, V., Echtay, A., & Fonseca, V. (2015). Triple combination of insulin glargine, sitagliptin and metformin in type 2 diabetes: The EASIE post-hoc analysis and extension trial. Journal of Diabetes and its Complications, 29(1), 134-141.
https://doi.org/10.1016/j.jdiacomp.2014.08.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26722
Thomas, R., Distiller, L., Luzio, S., Melville, V., Roy Chowdhury, S., Kramer, B., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2015). Incidence and progression of diabetic retinopathy within a private diabetes mellitus clinic in South Africa. Journal of Endocrinology, Metabolism and Diabetes of South Africa, 20(3), 127-133.
https://doi.org/10.1080/16089677.2015.1090159, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa23547
Hilgenfeld, R., Seipke, G., Berchtold, H., & Owens, D. (2014). The Evolution of Insulin Glargine and its Continuing Contribution to Diabetes Care. Drugs, 74(8), 911-927.
https://doi.org/10.1007/s40265-014-0226-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26725
Groop, P., Del Prato, S., Taskinen, M., Owens, D., Gong, Y., Crowe, S., Patel, S., von Eynatten, M., Woerle, H., & Owens, D. (2014). Linagliptin treatment in subjects with type 2 diabetes with and without mild-to-moderate renal impairment. Diabetes, Obesity and Metabolism, 16(6), 560-568.
https://doi.org/10.1111/dom.12281, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26726
Bolli, G., Owens, D., & Owens, D. (2014). Lixisenatide, a novel GLP-1 receptor agonist: efficacy, safety and clinical implications for type 2 diabetes mellitus. Diabetes, Obesity and Metabolism, 16(7), 588-601.
https://doi.org/10.1111/dom.12253, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26727
Thomas, R., Prior, S., Barry, J., Luzio, S., Eyre, N., Caplin, S., Stephens, J., Owens, D., & Thomas, B. (2014). Does bariatric surgery adversely impact on diabetic retinopathy in persons with morbid obesity and type 2 diabetes? A pilot study. Journal of Diabetes and its Complications, 28(2), 191-195.
https://doi.org/10.1016/j.jdiacomp.2013.10.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26728
Monnier, L., Colette, C., Dejager, S., Owens, D., & Owens, D. (2014). Residual dysglycemia when at target HbA1c of 7% (53mmol/mol) in persons with type 2 diabetes. Diabetes Research and Clinical Practice, 104(3), 370-375.
https://doi.org/10.1016/j.diabres.2014.03.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27111
Owens, D., Traylor, L., Dain, M., & Landgraf, W. (2014). Efficacy and safety of basal insulin glargine 12 and 24 weeks after initiation in persons with type 2 diabetes: A pooled analysis of data from treatment arms of 15 treat-to-target randomised controlled trials. Diabetes Research and Clinical Practice, 106(2), 264-274.
https://doi.org/10.1016/j.diabres.2014.08.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26723
Owens, D., Matfin, G., & Monnier, L. (2014). Basal insulin analogues in the management of diabetes mellitus: what progress have we made?. Diabetes/Metabolism Research and Reviews, 30(2), 104-119.
https://doi.org/10.1002/dmrr.2469, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27113
Owens, D. (2014). Guideline for management of postmeal glucose in diabetes. Diabetes Research and Clinical Practice, 103(2), 256-268.
https://doi.org/10.1016/j.diabres.2012.08.002, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27114
Thomas, R., Distiller, L., Luzio, S., Chowdhury, S., Melville, V., Kramer, B., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2013). Ethnic Differences in the Prevalence of Diabetic Retinopathy in Persons With Diabetes When First Presenting at a Diabetes Clinic in South Africa. Diabetes Care, 36(2), 336-341.
https://doi.org/10.2337/dc12-0683, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12272
Owens, D., Landgraf, W., Schmidt, A., Bretzel, R., & Kuhlmann, M. (2012). The Emergence of Biosimilar Insulin Preparations—A Cause for Concern?. Diabetes Technology Therapeutics, 14(11), 989-996.
https://doi.org/10.1089/dia.2012.0105, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13257
Owens, D., Prato, S., Taskinen, M., Gomis, R., Forst, T., Woerle, H., & Owens, D. (2012). Response Letter to D. Singh-Franco et al.. Diabetes, Obesity and Metabolism, 14(11), 1054-1055.
https://doi.org/10.1111/j.1463-1326.2012.01623.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13258
Owens, D. & Owens, D. (2012). Stepwise intensification of insulin therapy in Type 2 diabetes management-exploring the concept of the basal-plus approach in clinical practice. Diabetic Medicine, n/a-n/a.
https://doi.org/10.1111/dme.12019, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13268
Nosek, L., Cardot, J., Owens, D., Ibarra, P., Bagate, K., Vergnault, G., Kaiser, K., Fischer, A., Heise, T., & Owens, D. (2012). Modified release terbutaline (SKP1052) for hypoglycaemia prevention: a proof-of-concept study in people with type 1 diabetes mellitus. Diabetes, Obesity and Metabolism, n/a-n/a.
https://doi.org/10.1111/dom.12003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13269
Gomis, R., Owens, D., Taskinen, M., Prato, S., Patel, S., Pivovarova, A., Schlosser, A., Woerle, H., & Owens, D. (2012). Long-term safety and efficacy of linagliptin as monotherapy or in combination with other oral glucose-lowering agents in 2121 subjects with type 2 diabetes: up to 2 years exposure in 24-week phase III trials followed by a 78-week open-label extension. International Journal of Clinical Practice, 66(8), 731-740.
https://doi.org/10.1111/j.1742-1241.2012.02975.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13270
Aschner, P., Chan, J., Owens, D., Picard, S., Wang, E., Dain, M., Pilorget, V., Echtay, A., & Fonseca, V. (2012). Insulin glargine versus sitagliptin in insulin-naive patients with type 2 diabetes mellitus uncontrolled on metformin (EASIE): a multicentre, randomised open-label trial. The Lancet, 379(9833), 2262-2269.
https://doi.org/10.1016/S0140-6736(12)60439-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13273
Murthy, K., Murthy, P., Kapur, A., & Owens, D. (2012). Mobile diabetes eye care: Experience in developing countries. Diabetes Research and Clinical Practice, 97(3), 343-349.
https://doi.org/10.1016/j.diabres.2012.04.025, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13274
Yeo, S., Edwards, R., Luzio, S., Charles, J., Thomas, R., Peters, J., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2012). Diabetic retinopathy screening: perspectives of people with diabetes, screening intervals and costs of attending screening. Diabetic Medicine, 29(7), 878-885.
https://doi.org/10.1111/j.1464-5491.2012.03637., SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11754
Yeo, S., Edwards, R., Fargher, E., Luzio, S., Thomas, R., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2012). Preferences of people with diabetes for diabetic retinopathy screening: a discrete Choice experiment. Diabetic Medicine, 29(7), 869-877.
https://doi.org/10.1111/j.1464-5491.2012.03636.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11755
Thomas, R., Dunstan, F., Luzio, S., Chowdhury, S., Hale, S., North, R., Gibbins, R., Owens, D., Luzio, S., Owens, D., & Thomas, B. (2012). Incidence of diabetic retinopathy in people with type 2 diabetes mellitus attending the Diabetic Retinopathy Screening Service for Wales: retrospective analysis. BMJ, 344
https://doi.org/10.1136/bmj.e874, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa11753
Bolli, G., Luzio, S., Marzotti, S., Porcellati, F., Sert-Langeron, C., Charbonnel, B., Zair, Y., Owens, D., Luzio, S., & Owens, D. (2011). Comparative pharmacodynamic and pharmacokinetic characteristics of subcutaneous insulin glulisine and insulin aspart prior to a standard meal in obese subjects with type 2 diabetes. Diabetes, Obesity and Metabolism, 13(3), 251-257.
https://doi.org/10.1111/j.1463-1326.2010.01343.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10123
Owens, D., Luzio, S., Sert-Langeron, C., Riddle, M., Luzio, S., & Owens, D. (2011). Effects of initiation and titration of a single pre-prandial dose of insulin glulisine while continuing titrated insulin glargine in type 2 diabetes: a 6-month ‘proof-of-concept' study. Diabetes, Obesity and Metabolism, 13(11), 1020-1027.
https://doi.org/10.1111/j.1463-1326.2011.01459.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12264
Owens, D. (2011). International Forum for the Advancement of Diabetes Research and Care, April 29-30, 2011, Athens, Greece..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13280
Owens, D., Swallow, R., Dugi, K., Woerle, H., & Owens, D. (2011). Efficacy and safety of linagliptin in persons with Type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study1. Diabetic Medicine, 28(11), 1352-1361.
https://doi.org/10.1111/j.1464-5491.2011.03387.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13281
Owens, D. (2011). Insulin preparations with prolonged effect..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13282
Owens, D. (2011). Evaluation of an online interactive Diabetes Needs Assessment Tool (DNAT) versus online self-directed learning: a randomised controlled trial..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13283
Monnier, L., Colette, C., Michel, F., Cristol, J., & Owens, D. (2011). Insulin therapy has a complex relationship with measure of oxidative stress in type 2 diabetes: a case for further study. Diabetes/Metabolism Research and Reviews, 27(4), 348-353.
https://doi.org/10.1002/dmrr.1174, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13286
Luzio, S., Dunseath, G., Lockett, A., Broke-Smith, T., New, R., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2010). The glucose lowering effect of an oral insulin (Capsulin) during an isoglycaemic clamp study in persons with type 2 diabetes. Diabetes, Obesity and Metabolism, 12(1), 82-87.
https://doi.org/10.1111/j.1463-1326.2009.01146.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10122
Sharif, A., Ravindran, V., Dunseath, G., Luzio, S., Owens, D., Baboolal, K., & Luzio, S. (2010). Impending Hyperglycemia in Normoglycemic Renal Transplant Recipients—An Experimental Predictive Surrogate. Transplantation, 89(11), 1341-1346.
https://doi.org/10.1097/TP.0b013e3181d9e1d8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10973
Peter, R., Dunseath, G., Luzio, S., Chudleigh, R., Choudhury, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2010). Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes. Diabetic Medicine, 27(3), 266-273.
https://doi.org/10.1111/j.1464-5491.2010.02949.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10975
Sharif, A., Ravindran, V., Moore, R., Dunseath, G., Luzio, S., Owens, D., Baboolal, K., & Luzio, S. (2010). Insulin Resistance Indexes in Renal Transplant Recipients Maintained on Tacrolimus Immunosuppression. Transplantation, 89(3), 327-333.
https://doi.org/10.1097/TP.0b013e3181bbf2c4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10976
Owens, D. (2010). A longitudinal study into the new and long-term use of self-monitoring blood glucose strips in the UK..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13288
Owens, D. (2010). The pulse volume recorder as a measure of peripheral vascular status in people with diabetes mellitus..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13294
Owens, D. (2010). Prevalence of diabetic macular oedema and related health and social care resource use in England..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13285
Monnier, L., Colette, C., Mas, E., Michel, F., Cristol, J., Boegner, C., Owens, D., & Owens, D. (2010). Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy. Diabetologia, 53(3), 562-571.
https://doi.org/10.1007/s00125-009-1574-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13300
Monnier, L., Colette, C., Mas, E., Michel, F., Cristol, J., Boegner, C., Owens, D., & Owens, D. (2010). Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy. Diabetologia, 53(3), 562-571.
https://doi.org/10.1007/s00125-009-1574-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16337
Sharif, A., Ravindran, V., Dunseath, G., Luzio, S., Owens, D., & Baboolal, K. (2010). Impending Hyperglycemia in Normoglycemic Renal Transplant Recipients—An Experimental Predictive Surrogate. Transplantation, 89(11), 1341-1346.
https://doi.org/10.1097/TP.0b013e3181d9e1d8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13290
Chudleigh, R., Ollerton, R., Dunseath, G., Peter, R., Harvey, J., Luzio, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2009). Use of cystatin C-based estimations of glomerular filtration rate in patients with type 2 diabetes. Diabetologia, 52(7), 1274-1278.
https://doi.org/10.1007/s00125-009-1379-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9923
Peter, R., Dunseath, G., Luzio, S., Chudleigh, R., Choudhury, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2009). Relative and absolute contributions of postprandial and fasting plasma glucose to daytime hyperglycaemia and HbA1cin subjects with Type 2 diabetes. Diabetic Medicine, 26(10), 974-980.
https://doi.org/10.1111/j.1464-5491.2009.02809.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10980
Bretzel, R., Eckhard, M., Landgraf, W., Owens, D., Linn, T., & Owens, D. (2009). Initiating Insulin Therapy in Type 2 Diabetic Patients Failing on Oral Hypoglycemic Agents: Basal or prandial insulin? The APOLLO trial and beyond. Diabetes Care, 32(suppl_2), S260-S265.
https://doi.org/10.2337/dc09-S319, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16339
Owens, D. (2009). Integrating glycaemic variability in the glycaemic disorders of type 2 diabetes: a move towards a unified glucose tetrad concept.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13306
Owens, D. (2009). Postprandial glucose - a potential therapeutic target to reduce cardiovascular mortality..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13308
Bretzel, R., Eckhard, M., Landgraf, W., Owens, D., Linn, T., & Owens, D. (2009). Initiating Insulin Therapy in Type 2 Diabetic Patients Failing on Oral Hypoglycemic Agents: Basal or prandial insulin? The APOLLO trial and beyond. Diabetes Care, 32(suppl_2), S260-S265.
https://doi.org/10.2337/dc09-S319, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13298
Sharif, A., Ravindran, V., Moore, R., Baboolal, K., Dunseath, G., Luzio, S., Owens, D., & Luzio, S. (2009). Complex Interplay Between Insulinemia, Glycemia, and Glomerular Filtration Rate in Nondiabetic Renal Transplant Recipients. Transplantation, 88(2), 290-292.
https://doi.org/10.1097/TP.0b013e3181acc901, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12479
Ravindran, V., Moore, R., Dunseath, G., Luzio, S., Owens, D., Baboolal, K., & Luzio, S. (2009). Insulin Hyposecretion in Nondiabetic, Tacrolimus-Treated Renal Transplant Recipients More Than 6 months Posttransplantation. Transplantation, 87(12), 1870-1876.
https://doi.org/10.1097/TP.0b013e3181a767b3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10480
http://www.scopus.com/inward/record.url?eid=2-s2.0-67649610585&partnerID=MN8TOARS
Chudleigh, R., Dunseath, G., Peter, R., Dunseath, G., Luzio, S., & Owens, D. (2008). Influence of body weight on the performance of glomerular filtration rate estimators in subjects with type 2 diabetes. Diabetes Care, 31, 47-49.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa9922
Chudleigh, R., Ollerton, R., Dunseath, G., Peter, R., Harvey, J., Luzio, S., Owens, D., Dunseath, G., Luzio, S., & Owens, D. (2008). Performance of the revised ‘175’ Modification of Diet in Renal Disease equation in patients with type 2 diabetes. Diabetologia, 51(9), 1714-1718.
https://doi.org/10.1007/s00125-008-1086-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10120
Owens, D. (2008). Beyond the era of NPH insulin--long-acting insulin analogs: chemistry, comparative pharmacology, and clinical application..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13309
Owens, D. (2008). Type 2 diabetes: a well-characterised but suboptimally controlled disease. Can we bridge the divide?.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13312
Bretzel, R., Nuber, U., Landgraf, W., Owens, D., Bradley, C., & Linn, T. (2008). Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial. The Lancet, 371(9618), 1073-1084.
https://doi.org/10.1016/S0140-6736(08)60485-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13313
Owens, D. (2008). Glycemic variability: the third component of the dysglycemia in diabetes. Is it important? How to measure it?.
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13301
Owens, D. (2008). Consensus report of the coalition for clinical research-self-monitoring of blood glucose..
SU Repository: https://cronfa.swan.ac.uk/Record/cronfa13302
Conley, E., Owens, D., Luzio, S., Subramanian, M., Ali, A., Hardisty, A., & Rana, O. (2008). Simultaneous trend analysis for evaluating outcomes in patient-centred health monitoring services. Health Care Management Science, 11(2), 152-166.
https://doi.org/10.1007/s10729-008-9061-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12481
Luzio, S., Peter, R., Dunseath, G., Mustafa, L., & Owens, D. (2008). A comparison of preprandial insulin glulisine versus insulin lispro in people with Type 2 diabetes over a 12-h period. Diabetes Research and Clinical Practice, 79(2), 269-275.
https://doi.org/10.1016/j.diabres.2007.11.013, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12482
Landgraf, W., Owens, D., Frier, B., Zhang, M., & Bolli, G. (n.d.) Fasting C‐peptide, a biomarker for hypoglycaemia risk in insulin‐naïve people with type 2 diabetes initiating basal insulin glargine 100 U/mL. Diabetes, Obesity and Metabolism
https://doi.org/10.1111/dom.13897, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52651
http://dx.doi.org/10.1111/dom.13897
Monnier, L., Wojtusciszyn, A., Molinari, N., Colette, C., Renard, E., & Owens, D. (n.d.) Respective Contributions of Glycemic Variability and Mean Daily Glucose as Predictors of Hypoglycemia in Type 1 Diabetes: Are They Equivalent?. Diabetes Care, dc191549
https://doi.org/10.2337/dc19-1549, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53212
Monnier, L., Colette, C., Bonnet, F., & Owens, D. (n.d.) Number Needed-to-Treat (NNT): Is it a necessary marker of therapeutic efficiency?. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2020.01.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53471
Monnier, L., Colette, C., & Owens, D. (n.d.) Application of medium-term metrics for assessing glucose homoeostasis: Usefulness, strengths and weaknesses. Diabetes & Metabolism
https://doi.org/10.1016/j.diabet.2020.06.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54460

Book Chapters

Xu, W., Owens, D., & Weng, J. (2014). Short-Term Intensive Insulin Therapy in Persons with Newly Presenting Type 2 Diabetes Mellitus. Endocrine and Metabolic Medical Emergencies: A Clinician's Guide-278). Endocrine Press
https://doi.org/10.1210/EME.9781936704811.ch27, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34718
http://press.endocrine.org/doi/book/10.1210/EME.9781936704811

Conference Contributions

Noyel, G., Thomas, B., Iles, S., Bhakta, G., Crowder, A., Owens, D., & Boyle, P. (2019). Registration Of Retinal Images From Public Health By Minimising An Error Between Vessels Using An Affine Model With Radial Distortions. In 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019) (pp. 561-564). IEEE.
https://doi.org/10.1109/isbi.2019.8759415, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52801